Automatic Vial Bottle Pharmaceutical Liquid Filling and Screwing Capping Machine

short description:

The vial filling line is composed of bottle unscrambler, rough washing machine, fine washing machine, filling and stoppering machine, capping machine. It can complete bottle unscrambling, rough washing, fine washing, nitrogen filling, vacuumize, stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately or in linkage line. The whole line is mainly used for production of sterile glass bottle IV infusions, and also final sterilized drugs.

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Overview

The vial filling production line is composed of ultrasonic bottle washing machine, dryer sterilizer, filling stoppering machine, and capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.

Parameter

Model	SHPD4	SHPD6	SHPD8	SHPD10	SHPD12	SHPD20	SHPD24
Applicable specifications	2~30ml vial bottles
Filling heads	4	6	8	10	12	20	24
Production capacity	50-100bts/min	80-150bts/min	100-200bts/min	150-300bts/min	200-400bts/min	250-500bts/min	300-600bts/min
Stoppling qualification rate	>=99%
Laminar air cleanliness	100 grade
Vacuum pumping speed	10m3/h	30m3/h	50m3/h	60m3/h	60m3/h	100m3/h	120m3/h
Power consumption	5kw
Power supply	220V/380V 50Hz

Machine configuration

Frame	SUS304 Stainless steel
Parts in contact with liquid	SUS316L Stainless steel
Electrical parts
Pneumatic part

Features

1.The vial filling sealing production line meets new GMP requirements, and the cleaning effect meets the new Pharmacopoeia standards and requirements.
2.The whole line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level.
3.Applicable specification: 1ml-100ml vial (as per user's requirement)
4.Production Capacity: 1000-36000BPH
5.Number of filling head: 1-20, to be selected according to the output
6.Filling Accuracy of vial filling machine: ≤ ±1% (according to drug characteristics)
7.Choice of various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;
8.Capping qualified rate: ≥99.9%
9.Compact and simple structure, occupies less area;
10.Stable product performance, easy and reliable operation, beautiful appearance;
11.High degree of automation, few operators required;

Working Process

The incoming dry vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of S.S. 316 construction and both, glass as well as S.S. syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided.

The Machine Details

1)This is filling pipes, it is high quality imported pipes.There are the valves on the pipe, it will suck liquid back after once filling. So filling nozzles will not leakage.

2) The multi roller structure of our peristaltic pump further improves the stability and non impact of filling and makes the liquid filling stable and not easy to blister. It is especially suitable for filling the liquid with high requirement.

3)This is aluminum Cap sealing head. It has three sealing roller. It will sealing Cap from four sides, so the sealed Cap is very tighten and beautiful. It will not damage Cap or leakage Cap.